Scientific Proof

Umbilical Cord Blood in Medicine

Umbilical cord blood is a valuable resource for treating various blood disorders due to the presence of stem cells. These stem cells can form all types of blood cells when needed, making them useful for restoring blood formation and the immune system after intensive chemotherapy or radiation therapy.

To date, umbilical cord blood has been used to treat approximately 80 diseases, including various cancers, blood disorders, and immune system disorders (source: https://www.ebmt.org/education/ebmt-handbook)

Due to the unique properties of stem cells, umbilical cord blood also serves as a foundation for developing new, innovative therapies.

List of medical conditions treated with stem cells

Acute leukaemias

Acute lymphoblastic leukaemia (ALL)

Acute biphenotipic leukaemia

Acute myeloid leukaemia (AML)

Poorly differentiated acute leukaemia

Chronic leukaemias

Chronic myeloid leukaemia (CML)

Chronic lymphocytic leukaemia (CLL)

Juvenile chronic myeloid leukaemia (JCML)

Juvenile myelomonocytic leukaemia (Naegeleg leukaemia) (JMML)

Myelodisplastic syndrome

Refractory anaemia (RA)

Refractory anaemia with excess blasts (RAEB)

Refractory anaemia with ringed sideroblasts (RARS)

Refractory anaemia with excess blasts in transformation (RAEB-T)

Chronic myelomonocytic leukaemia (CMML)

Diseases caused by stem cell defect

Aplastic anaemia(severe)

Paroxysmal nocturnal haemoglobinuria

Fanconi anaemia

Myeloproliferative syndromes

Acute myelofibrosis

Polycythaemia vera

Myelofibrosis

Essentials thromb ocythemia

Hyperplastic disorders of lymphatic system

Non-Hodgkin lymphoma

Prolimphocytic leukaemia

Acute lymphogranuloma

Phagocytic disorders

Chediak-Higashi syndrome

Neutrophil actin dysfunction

Chronic granulomatous disease (CGD)

Reticular dysgenesis

Disorders caused by the absence or malfunctioning of enzymes

Mucopolysaccharidoses (MPS)

Adrenoleukodystrophy

Scheie syndrome (MPS-IS)

Mucolipidosis II

Hunter syndrome(MPS-II)

Krabbe disease

Sanfilippo syndrome (MPS-III)

Gaucher disease

Morquio syndrome (MPS-IV)

Niemann-Pick disease

Maroteaux-Lamy syndrome (MPS-VI)

Wolman disease

Sly syndrome, beta- glucoronidase deficiency (MPS-VII)

Metachromatic leukodystrophy

Histiocytic disorders

Familial erythrophagocytic lymphohistiocytosis

Hemophagocytosis

Histiocytosis -X

Inherited red blood cell abnormalities

Beta thalassemia

Sickle cell anaemia

Pure red cell aplasia

Inherited immune system disorders

Telangiectasia

SCID adenosine deaminase deficiency

Kostmann syndrome

SCID T and B lymphocytes negative

Leukocyte adhesion deficiency

SCID T lymphocytes negative and B lymphocytes positive

DiGeorge syndrome

Common variable immunodeficiency

Bare lymphocyte syndrome

Wiskotta Aldrich syndrome

Omenn syndrome

X-linked lymphoproliferative disorder

Severe combined immunodeficiency (SCID)

Other inherited conditions

Lesch-Nyhan syndrome

Glanzmann’s thrombasthenia

Cartilage-hair hypoplasia

Osteopetrosis (marble bone disease)

Hereditary thrombotic disorders

Mega-karyocytosis (inherited thrombocythemia)

Plasma cell disorders

Multiple myeloma

Waldenström’s macroglobulinemia

Plasmocythic leukaemia

Other forms of cancer

Breast cancer

Neuroblastoma

Ewing’s sarcoma

Kidney cancer

Important Notice: The diseases listed here have been demonstrably treated using umbilical cord blood. However, the decision to use stored umbilical cord blood is made individually by the treating physician based on the specific disease situation and available treatment options.